I've been using this for about a year and no problems. I guess it was anti biotics that gave my stomach problems. I take 2 or 3 after a meal, if I feel like I need it. I really like it at night when my stomach is a little upset, This works great!
I really liked the Papaya Digestive Support because it works on my heartburn. I tried the Tums route but no relief so I bought a bottle of the Papaya Digestive Support from my local food store. I decided to look at iHerb and found that I could get "two" bottles for the price I was paying just for one. I found if I took the Papaya Digestive Support, I build up the enzyme in my stomach and now keep up with it at least once a week and no more heartburn!