I take this together with l-ornithine and larch arabinogalactan to lower ammonia. Other supplements like chlorophyll, l-arginine, l-citrulline, l-glutamine, celery juice, bentonite clay are also helpful, but i didn't try all of them. If you have too much ammonia in the body and brain, i recommend to take daily yucca. Too mucah ammonia is toxic. Since i take yucca, i feel more energy and have less headache and feel less 'drunk'. My head feels more clear.
I have used this product for many years for two different dogs with joint problems. It works great. One was an older dog and he move around like a young dog. The other one was born with floating patellas and they never became a problem because we have been giving him Yucca since he was a puppy. It is a lot better for them that the prescription drugs and do not have the side effects.
I use Yucca to detoxify excess ammonia caused by the CBS mutation. Can't really notice any difference. Have found that the Yucca hardens in the capsules once the seal is broken, so don't know if that affects the efficacy of the Yucca. Would probably recommend The Nature's Answer Yucca in the liquid form over the capsules. Also has the advantage of fine tuning the dose.